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PENICILLIN: THE FIRST TRUE ANTIBIOTIC!!!

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Hi Folks!! Follow our blog on Instagram Penicillin is a group of antibiotics derived from Penicillium fungi. Discovered by Alexander Fleming in 1928, penicillin revolutionized medicine by providing the first effective treatment against bacterial infections. Discovery: Alexander Fleming, a Scottish bacteriologist, discovered penicillin in 1928 while studying Staphylococcus bacteria. He noticed that a mold, Penicillium notatum , had contaminated one of his petri dishes and inhibited bacterial growth around it. Development: Fleming's discovery didn't lead directly to the widespread use of penicillin. It was further developed by Howard Florey, Ernst Boris Chain, and their team at the University of Oxford during the 1930s and 1940s. They successfully purified penicillin and demonstrated its effectiveness in treating bacterial infections. Types of Penicillin: Natural Penicillins: These are penicillins produced directly from the Penicillium mold. Examples i

MR & MRS ANTOINE LAVOISER AND THEIR CONTRIBUTION TO SCIENCE

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Hi Folks!! Follow our blog on instagram LAB IN THE BOX MR & MRS ANTOINE LAVOISER AND THEIR CONTRIBUTION TO SCIENCE Antoine Lavoisier, often referred to as the "Father of Modern Chemistry," made numerous significant contributions to science during the 18th century, particularly in the fields of chemistry and biology. Here are some of his main contributions: Law of Conservation of Mass: Lavoisier is best known for his experimental work that led to the formulation of the Law of Conservation of Mass. Through meticulous experimentation, he demonstrated that in a chemical reaction, the total mass of the reactants is equal to the total mass of the products. This laid the foundation for modern chemistry and overturned the previous theory of phlogiston. Oxygen Theory of Combustion : Lavoisier conducted extensive studies on combustion and oxidation processes. He demonstrated that combustion is not the liberation of a substance called phlogiston, as previously believed, but rather

China's First ever CRISPR Cas9 system Patent!

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Hi Folks!! Follow our blog on  Instagram China’s patent and trademark office has upheld a key patent within the portfolio of CRISPR/Cas9 intellectual property belonging to Nobel Laureate Emmanuelle Charpentier, The Regents of the University of California, and University of Vienna (known collectively as CVC), and licensed for commercial use through ERS Genomics. Dublin-based ERS Genomics said the China National Intellectual Property Administration (CNIPA) has upheld Patent No. CN201380038920.6, “Methods and Compositions for RNA-guided Target DNA Modification and for RNA-guided Transcription Regulation”. ToolGen claims that it was the  world’s first  filer of patents covering gene editing in eukaryotic cells using the CRISPR-Cas9 system. “The decision by the CNIPA fully upholding the patent further demonstrates its validity and value as part of the patent collection for use of the CRISPR/Cas9 technology,” ERS Genomics stated in announcing the Chinese decision recently. The CVC patents ha

"UNVEILING THE VITAL ROLE OF MULLER-HINTON AGAR IN ANTIBIOTIC SUSCEPTIBILITY TESTING"

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Hi Folks!! Follow our blog on Instagram LAB IN THE BOX Muller-Hinton agar is a specialized growth medium commonly used in microbiology to culture and test the susceptibility of bacteria to antibiotics. It was developed by John Hinton and Jane Muller in 1941. The composition of Muller-Hinton agar is optimized to provide a uniform medium for bacterial growth and to allow accurate antibiotic susceptibility testing. It typically contains beef infusion, casein hydrolysate, and starch, along with agar as a solidifying agent. Importantly, the medium has a low content of calcium and magnesium ions, which can interfere with the action of certain antibiotics. One of the key features of Muller-Hinton agar is its pH level, which is maintained around 7.2-7.4. This pH range is ideal for the growth of most bacteria and ensures consistent results in susceptibility testing. Muller-Hinton agar is particularly well-suited for the Kirby-Bauer disk diffusion method, a standard technique used to determine t